Clin Res Cardiol 103, Suppl 1, April 2014

P800 - Analysis of drugs stored at home by elderly patients with chronic heart failure
S. Ewen1, T. Baumgarten1, V. Rettig-Ewen2, F. Mahfoud1, M. Schulz3, M. Böhm1, U. Laufs1
1Klinik für Innere Medizin III, Kardiologie und Angiologie, Universitätsklinikum des Saarlandes, Homburg/Saar; 2Schwemmlinger Gemeinschaftspraxis, Merzig; 3Vorsitzender, Arzneimittelkommission der Deutschen Apotheker (AMK), Berlin;
Background: Chronic heart failure (CHF) is one of the most common chronic diseases. Evidence-based pharmacotherapy to improve morbidity and mortality requires the chronic self-administration of multiple drugs. Moreover, several co-morbidities of the CHF patient typically result in complex polypharmacy. Medication management and adherence to CHF medication is an increasingly important component for the effectiveness and safety of the treatment especially in elderly patients.
Methods: This study investigated the quantity of drugs stored at home, collecting medical, functional, and psychosocial characteristics of patients aged ≥ 65 years with CHF. 
Results: One-hundred-and-one patients were visited at their home where a standardized interview and a thorough assessment of the complete medication were performed. Mean age of the patients was 77.7 years, 53% women, mean NYHA functional class of 2.75 and a Minnesota Living with Heart Failure score of 59.4 points, indicating poor quality of life. The mean number of different drug packs found at home was 13.1 per patient (range 4-33, mean costs per patient of approximately 383 €). Cardiovascular drugs accounted for 32% of the packs (30% of total costs). On average, 2.4 packs contained medication that was not taken by the patient (18% of the medication, range 0-10, mean costs 61 €). Fifty-six percent of the drugs were prescribed by general practitioners, 23% in the hospital, and 17% by medical specialists while 14% were over-the-counter drugs. Sixty-three packages (0.05%) of the drugs found at home were expired (mean costs 12 € per patient).
Conclusion: On average, the elderly patient with CHF has to manage ~13 different drug packs at home. New strategies are needed to improve both medication adherence, hence effectiveness, and drug safety as well as to avoid the significant waste of unused drugs.
Clin Res Cardiol 103, Suppl 1, April 2014
Zitierung mit Vortrags- oder Posternummer s.o.
DOI 10.1007/s00392-014-1100-9